Cancer concerns one out of two men and one out of three women.
Cancer is a genetic disorder.
Pronostic and treatment depend on the genes involved.
BUT 2 000 to 9 000 genes may be involved in cancer!

• The Atlas of genetics in cancer is an encyclopedic database made of more than 45,000 pages written by more than 3,500 experts. It is also an international journal.

• The Atlas is an information resource for doctors, researchers, teachers and students, accessed by over 4 600 people for 5 500 visits each day, 1.1 million unique users a year.

• The Atlas is in free access on the Internet at: AtlasGeneticsOncology.org.

What is the Atlas?

Cancer Genetics, a fast developping field, merits more than 200,000 pages

Cancer, the second cause of death in the developed countries, is the first cause of untimely death. Prognosis of a leukaemia, for instance, depends on the genes involved... However, about 4,500 genes are possibly implicated in cancer! Therefore, there is a need for huge databases collecting and summarising the fast growing knowledge accumulated in cancer genetics (see, for more details: Why the Atlas?).

The Atlas is a peer-reviewed journal / encyclopaedia / internet database aimed at genes involved in cancer, cytogenetics and leukemias, solid tumours, and cancer-prone diseases. It also comprises educational items in genetics for students.

Structure of the Atlas

The Atlas is mainly made of structured review articles or "cards" (see above), but it also contains traditional overviews, a huge portal towards websites and databases devoted to cancer and/or genetics, case reports in haematology, and, as we have said, teaching items in various languages.

Cards are structured: e.g. cards on genes are made of the following paragraphs:
1- identity
2- DNA/RNA
3- protein
4- diseases where the gene is involved
5- external links
6- bibliography.

Deep Insights: these review articles are more traditional papers; they often deal with various themes at the outskirts of our core topic.

Portal: it comprises about 275 links:
1- general links (bibliography, general resources)
2- databases in genetics
3- resources in cancer genetics and cytogenetics
4- mapping resources
5- chromosomes maps (mouse, man)
6- functional genomic, transcriptome
7- journals.

A collective effort

The Atlas is a collective effort from researchers and clinicians to give the state of the art in cancer genetics to the medical and scientific community, to provide a cognitive tool for fundamental and clinical research. Readers of the Atlas are consultants at the hospital, researchers, university teachers, but it also reaches GP's, students in medicine, and students in sciences.

The genome project

The Atlas is part of the genome project and it participates in research on cancer epidemiology. It is at the crossroads of research, university and post-university teaching (e-learning, virtual medical university) and telemedicine, using new information and communication technologies. It contributes to meta-medicine, this mediation between the overflowing information provided by the scientific community and the individual practitioner. It helps the clinician in therapy decision. Its reputation is international.

The Atlas is free, in particular for third world countries.

• Founded in 1993,

  the association ARMGHM - Atlas Génétique des Cancers - is a not-for-profit organization

  under French law (law 1901), whose purpose is to host the Atlas of Cancer Genetics, to facilitate its editorial process and to ensure the propagation of its contents.

• It is necessary to sustain the Atlas. Funding is essential for the maintenance and continuous updating and development of the site.

• Over 90% of our operating expenses between 2008 and 2015 has gone to salary support for MSc or Phd Editorial Officers in charge of finding matters of study and their appropriate authors, and processing and editing papers (see Activity Reports).

The Atlas needs money,

to continue to assist medical and scientific community

PLEASE, MAKE A DONATION

... and If you use the Atlas regularly,

Become a member of the Association, for 30 euros or 40 dollars only

Use Paypal to pay and become a member. Specify in the "purpose" box that the payment is for membership.

Membership from cytogenetics labs are welcome,
for 100 euros or dollars (or much more, indeed)

We offer you a free service,

Please, help in return

Program

Enrichment with more cards

Development of the research side

- The Atlas participates in research on cancer epidemiology.

- The Atlas is part of the genome project. It is orientated towards the genome and may serve as a portal for many applications, from probes resources to genome sequences. At a time where maturation therapies and other oncogene-targeted therapies are being developed, the Atlas and its links make sense in the bioinformatics field.

Diagnostic and therapeutic decision aid

The Atlas helps the clinician in the diagnostic and in the patient treatment process: the iconography of chromosome anomalies can be compared by the cytogeneticist with his findings in a given patient, guiding his diagnosis. Next step, the clinician with a cytogenetic diagnosis may be helped by the description of the associated disease. In any case, the clinician ignores the prognostic associated with the chromosome findings in many cases (there are more than 600 leukemias!), and the Atlas would guide his treatment decision: a bone marrow graft may kill, it should be reserved for highly aggressive leukemias, and that risk must not be taken when the leukaemia would be cured in any case. The Atlas is indispensable in particular in rare diseases (and rare diseases, because they are numerous, are frequent). We must continue to develop this part.

Informatics developments

Atlas web site becoming a true database - from old html to xml: the Atlas is supported by an ancient html system, made in 1997, at a time where Internet was a starting technology (we were one of the pioneers !). Systems have evolved, since. A modern data base will soon replace our old html.

Enhancement of the Atlas position in the scientific literature world:

We have therefore developed an 'electronic journal' version of the Atlas, comprising 2 154 articles in 87 issues from 1998 making 7 169 pages. See: http://documents.irevues.inist.fr/handle/2042/15655 .

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Activity reports / Rapports d'activité / Informes de actividad

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Scientific board

Our scientific board includes:

• Dr Chrystèle BILHOU-NABERA, University Paris Sud and University Hospital of Le Kremlin Bicètre

• Dr Christian HERENS, University  of Liège, University Hospital of Sart Tilman, Liège

• Dr Claude VIGUIE, University Hospital of Cochin, Paris

• Dr Franck VIGUIE, University Paris V and University Hospital of Saint antoine, Paris

• M François DESANGLES, Val de Grâce Hospital of the Armed Forces, Paris

• M Hossain MOSSAFA, CERBA Laboratory, Cergy Pontoise

• Dr Jean Loup HURET, University et University Hospital of Poitiers

• Pr Jean-Michel DUPONT, University Paris Descartes and University Hospital of Cochin Broca Hôtel Dieu, Paris

• Pr Lucienne MICHAUX, Katholieke Universiteit Leuven, Leuven

• Pr Marc DE BRAEKELEER, University and University Hospital of Brest

• Dr Marina LAFAGE, University of Marseille and University Hospital of la Timone, Marseille

• Dr Pascaline TALMANT, University Hospital of Nantes

• Dr Nathalie NADAL, University Hospital of Dijon

• Dr Dominique PENTHER, CLCC Rouen, (ACLF and GFCH)

Support committee of the
Atlas of Genetics and Cytogenetics in Oncology and Haematology
http://atlasgeneticsoncology.org

Anh Dao TRAXEL, Foster daughter of Jacques CHIRAC, President of the Etoile Européenne du Dévouement Civil et Militaire (cf. http://www.eedcm.com),
President of the support committee

Patricia ARNAULT, Chair of the Department Physiology and Neurosciences, University of Poitiers, Associate Professorien Neurophysiology

Marie-Christine BOLINCHES, Agent general MEDEF Vienne

Anthony BROUARD, Senior Auditor in a Public Accounting Cabinet

Philippe CHARTIER, President of the chamber of commerce and industry of Vienne, President of the supervisory board of Polyclinique of Poitiers, President of the Ligue against Cancer of Vienne

François DESANGLES, Geneticist, Val de Grâce Hospital of the Armed Forces

Bernard DROCHON, External Auditor, Expert in Law Courts

Jean Loup HURET, Associate Professor and Consultant, University and CHU of Poitiers

Martine JAMMET, President of JMFret, Vice Presidente of Polyglotta, Member of the chamber of commerce and industry of Vienne, City Councillor of Poitiers

Philippe MISSEREY, Associate Lawyer, LELOUP Law Firm

Hossein MOSSAFA, Geneticist in Onco-Hematology, CERBA Laboratory

Jean Marie NICOLAS, President of the Commercial Court of Evry

Alain TEXIER, Agent General Resarch and Technology Poitou-Charentes

Franck VIGUIE, Associate Professor and Consultant, Paris Descartes University and Haematology Department, Hôpital St Antoine, AP-HP

Françoise VILAIN, Member of the Economic, Social and Environmental Council, President of the Enterprises' Group

Jacques WINTREBERT, Retired; previously Founder, Consultant and Associate and Chairman of PROTOURISME, Employers Association Leader, Teatcher...

Anh Dao TRAXEL

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